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El episodio de esta semana lo dedicamos a comentar ciertas controversias y recomendaciones sobre el tratamiento de infecciones urinarias.

Referencias:

1. Ainsley Moore y colaboradores. Canadian Task Force on Preventive Health Care Recommendations on screening for asymptomatic bacteriuria in pregnancy. CMAJ 2018 July 9;190:E823-30. doi: 10.1503/cmaj.171325.
2. The role of asymptomatic bacteriuria in young women with recurrent urinary tract infections: to treat or not to treat? Cai et al . Clin Infect Dis 2012: 55: 772-777. 
3. .Asymptomatic bacteriuria treatment is associated with a higher prevalence of antibiotic resistant strains in women with urinary tract infection. Cai et al. Clin Infect Dis 2015; 61: 1655-1661.
4. Krumpe PE, Cohn S, Garreltes J, et al. Intravenous and oral mono- or combination-therapy in the treatment of severe infections: ciprofloxacin versus standard antibiotic therapy. J Antimicrob Chemother. 1999;43(suppl A):117-128.
5. Sandberg T, Skoog G, Hermansson AB, et al. Ciprofloxacin for 7 days versus 14 days in women with acute pyelonephritis: a randomised, open-label and double-blind, placebo-controlled, non-inferiority trial. Lancet. 2012;380(9840):484-490. doi: 10.1016/S0140-6736(12)60608-4.
6. Talan DA, Stamm WE, Hooton TM, et al. Comparison of ciprofloxacin (7 days) and trimethoprim-sulfamethoxazole (14 days) for acute uncomplicated pyelonephritis pyelonephritis in women: a randomized trial. JAMA. 2000;283(12):1583-1590.
7. Kutob LF, Justo JA, Bookstaver PB, Kohn J, Albrecht H, Al-Hasan MN. Effectiveness of oral antibiotics for definitive therapy of Gram-negative bloodstream infections. Int J Antimicrob Agents. 2016;48(5):498-503. doi: 10.1016/j.ijantimicag.2016.07.013.
8. Mercuro NJ, Stogsdill P, Wungwattana M. Retrospective analysis comparing oral stepdown therapy for enterobacteriaceae bloodstream infections: fluoroquinolones versus beta-lactams. Int J Antimicrob Agents. 2018;51(5):687-692. doi: 10.1016/j.ijantimicag.2017.12.007.
9. Rieger KL, Bosso JA, MacVane SH, Temple Z, Wahlquist A, Bohm N. Intravenous-only or intravenous transitioned to oral antimicrobials for Enterobacteriaceae-associated bacteremic urinary tract infection. Pharmacotherapy. 2017;37(11):1479-1483. doi: 10.1002/phar.2024.
10. Nelson AN, Justo JA, Bookstaver PB, Kohn J, Albrecht H, Al-Hasan MN. Optimal duration of antimicrobial therapy for uncomplicated Gram-negative bloodstream infections. Infection. 2017;45(5):613-620. doi: 10.1007/s15010-017-1020-5.

La Frase de la Semana:

Esta semana la tomamos del escrito español Chufo Llorens.

Y la frase dice:

La distancia es al amor lo que el viento al fuego: apaga el pequeño, pero aviva el grande.